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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Cell Signal. 2012 Mar 10;24(7):1398–1405. doi: 10.1016/j.cellsig.2012.03.001

FIGURE 4. Methylphenidate treatment for eight days mimics amphetamine-induced alterations in phosphorylation of Akt and GSK3 in the striatum.

FIGURE 4

A. Treatment with 20 mg/kg methylphenidate for eight days reduced striatal phosphorylation of Thr308-Akt and Ser473-Akt. B. Phospho-Ser21-GSK3α and phospho-Ser9-GSK3β were reduced in striatum after methylphenidate treatment for eight days. Values are presented as percent of matched control mice. Means ± SEM. n=3. *, p≤0.05.