Fig. 2. Shh and IL-1β expression in control and PC-Shh^KO H. pylori-infected mouse stomachs.

RNA was extracted from stomachs of uninfected (open bars, W/O HP) and H. pylori-infected (closed bars, W/ HP) control and PC-Shh^KO (KO) mice 2, 7 and 180 days post-inoculation. Quantitative RT-PCR was performed and average fold change in gene expression is shown for Shh from RNA collected from (A) control and (B) PC-Shh^KO; IL-1β from RNA collected from (C) control and (D) PC-Shh^KO; Data is shown as the mean + SEM, n = 4 mice/group, *P<0.05 compared to uninfected group (W/O HP).