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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Br J Dermatol. 2012 Apr 4;166(5):1107–1111. doi: 10.1111/j.1365-2133.2012.10811.x

Figure 2.

Figure 2

PXE-like cutaneous findings and mutation analysis. The 2-year old patient demonstrates characteristic skin lesions on the side of the neck (a, asterisk), which histopathologically by von Kossa staining reveal ectopic mineralization in the dermis (b, arrowheads). Mutation analysis of the ENPP1 gene reveals a codon for tyrosine in position 513 in control DNA (c), which is replaced in the patient’s DNA by a codon for cysteine (d), confirming the diagnosis of generalized arterial calcification of infancy.