Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2013 May 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2012 Mar 18;260(3):285–293. doi: 10.1016/j.taap.2012.03.006

Fig. 5 — Tet-induced overexpression of CTR1 in iZCTR1 cells and the ensuing increase of cellular ⁶⁴Cu uptake. The iZCTR1 cells were treated with Tet at time “0”. (A) Time course of CTR1 mRNA expression following Tet induction. Data represent mean ± SE, n=6; *: p<0.05 as compared to controls. (B) Time course of CTR1 protein level following Tet addition. (C) Time course of the cellular ⁶⁴Cu uptake in iZCTR1 cells following Tet induction; the bar graph depicts the ⁶⁴Cu uptake of the “normal” Z310 cells treated with Tet for 24 h (n=6). Data represent Mean ± SE, n=6. **: p<0.01 compared to controls and the Tet-treated Z310 cells.

Fig. 5 — Tet-induced overexpression of CTR1 in iZCTR1 cells and the ensuing increase of cellular ⁶⁴Cu uptake. The iZCTR1 cells were treated with Tet at time “0”. (A) Time course of CTR1 mRNA expression following Tet induction. Data represent mean ± SE, n=6; *: p<0.05 as compared to controls. (B) Time course of CTR1 protein level following Tet addition. (C) Time course of the cellular ⁶⁴Cu uptake in iZCTR1 cells following Tet induction; the bar graph depicts the ⁶⁴Cu uptake of the “normal” Z310 cells treated with Tet for 24 h (n=6). Data represent Mean ± SE, n=6. **: p<0.01 compared to controls and the Tet-treated Z310 cells.