TABLE 8.

Logistic Regression Modeling Without and With Risk Genes

	Without Risk Genes in Model		With Risk Genes in Model
	OR 95% CI	P-value	OR 95% CI	P-value
Age (<30 y/o vs. >=30 y/o)	3.88 (1.96–7.69)	<0.001	3.57 (1.71–7.46)	0.001
Gender (female vs. male)	0.56 (0.37–0.85)	0.006	0.58 (0.37–0.91)	0.02
Residency (urban vs. rural)	1.01 (0.68–1.49)	0.98	1.05 (0.68–1.62)	0.82
Positive family history of IBD	2.41 (1.31–4.42)	0.005	2.75 (1.42–5.31)	0.003
Tobacco use	1.84 (1.25–2.71)	0.002	2.06 (1.35–3.14)	0.001
Jewish ethnicity	17.1 (2.12–138.3)	0.008	20.1 (2.16–186.8)	0.008
Carrier of NOD2 mutation	—		4.45 (2.68–7.38)	<0.001
Carrier of ATG16L1	—		1.88 (1.09–3.24)	0.02
Carrier of rs10889677	—		2.13 (1.39–3.28)	0.001
Carrier of IBD5_IGR2230	—		2.16 (1.30–3.59)	0.003