Fig. 3.

Representative data. a Pt. 1. Residual Grade 2 PD signals were detected in the wrist for at least 9 months (TIV-individual PD score was 33). Carpal joint-space narrowing and erosion of the ulnar head progressed throughout the study. b Pt. 5. After 2 courses of TCZ infusions PD signals decreased dramatically in each joint (TIV-individual PD scores of right 3PIP = 4.5, left 3PIP = 1.5, and left 3MCP = 8.5). No radiographic progression was seen in these joints. PIP proximal interphalangeal joint, MCP metacarpophalangeal joint