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. 2012 Jan 15;13(2):61–68. doi: 10.4161/cbt.13.2.18872

Figure 1.

Figure 1

Homologous recombination participates in resolution of two main types of double-strand breaks (DSBs) from endogenous and exogenous sources: (A) directly produced two-ended DSBs (like the ones produced by ionizing radiation) and (B) one-ended DSBs that result from single-strand breaks (SSBs) encountering replication forks. SSBs are common intermediates in the repair of many DNA lesions.