Figure 2.

Effect of calcium on AG1478-mediated tumor (A) number and (B) size in Apc^Min/+ and (C) tumor number in AOM models. Values are expressed as a percent of control treatment. Number of mice (A and C) and number of tumors (B) are displayed in bars of graph. Equal numbers of males and females were used and data for both sexes are shown. (C) A significant difference in tumor number is observed in AG1478 compared with Calcium/AG1478 treated mice only in females, but data for both sexes is shown. *p < 0.001; **p < 0.0001. Error bars show SEM.