Figure 3.

MTT assays of Caco-2 and HCT116 cell viability treated with AG1478 and/or calcium. (A) Calcium chloride and (B) AG1478 decrease cell viability compared with the control (no treatment) in a dose dependent manner. Supplementing a constant dose of AG1478 with increasing doses of calcium chloride results in reduced cell viability in an additive manner in both (C) Caco-2 and (D) HCT116 cells. Numbers within the bars indicate percent reduction when compared with control untreated cells. Error bars show SD.