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. 2012 Feb 1;13(3):164–174. doi: 10.4161/cbt.13.3.18698

Table 2.

Patient and tumor characteristics as predictors of survival

Univariate Cox model of major predictors
Covariate Hazard ratio p value
Genotype (A over C/C) 3.63 0.0004***
Lymph nodes (positive over negative) 2.03 0.037
Surgical margins (positive over negative) 0.663 0.332
Histologic grade (1,2,3 as continuous variable) 0.703 0.217
Age at diagnosis 0.982 0.2098
Adjuvant chemotherapy (no over yes) 0.748 0.3988
Gender (female over male) 0.723 0.3358
Diabetes (no over yes) 1.218 0.5761
Family history of pancreatic cancer (no over yes) 0.794 0.6388
Smoker (no over yes) 0.9858 0.994
Cox model of genotype and lymph nodes together
Covariate Hazard ratio p value
Genotype (A over C/C) 3.6 0.0005***
Lymph nodes (positive over negative) 2.0 0.05