Table 2.
Patient and tumor characteristics as predictors of survival
Univariate Cox model of major predictors | ||
Covariate | Hazard ratio | p value |
Genotype (A over C/C) | 3.63 | 0.0004*** |
Lymph nodes (positive over negative) | 2.03 | 0.037 |
Surgical margins (positive over negative) | 0.663 | 0.332 |
Histologic grade (1,2,3 as continuous variable) | 0.703 | 0.217 |
Age at diagnosis | 0.982 | 0.2098 |
Adjuvant chemotherapy (no over yes) | 0.748 | 0.3988 |
Gender (female over male) | 0.723 | 0.3358 |
Diabetes (no over yes) | 1.218 | 0.5761 |
Family history of pancreatic cancer (no over yes) | 0.794 | 0.6388 |
Smoker (no over yes) | 0.9858 | 0.994 |
Cox model of genotype and lymph nodes together | ||
Covariate | Hazard ratio | p value |
Genotype (A over C/C) | 3.6 | 0.0005*** |
Lymph nodes (positive over negative) | 2.0 | 0.05 |