Table 1.
Interactions of S100 proteins with ion channels1.
| S100 protein | Ion channel |
Other channels receptors | Reference | |||
|---|---|---|---|---|---|---|
| Na+ | K+ | Ca2+ | Cl− | |||
| S100A1 | heart, T-type | Reppel et al. (2005) | ||||
| in rods | Pozdnyakov et al. (1997), Rambotti et al. (1999), Duda et al. (2002) | |||||
| Art. memb. | Garbuglia et al. (2000), Arcuri et al. (2002) | |||||
| SR | Díaz-Muñoz et al. (1990), Treves et al. (1997) | |||||
| RyR/L-type | Prosser et al. (2008, 2010), Wright et al. (2008), Most et al. (2003) | |||||
| in neurons (SCG) | Hernández-Ochoa et al. (2009) | |||||
| S100B | Kv/hEAG1 | in rods | Dopamine D2 | Pozdnyakov et al. (1997), Rambotti et al. (1999), Duda et al. (2002), Sahoo et al. (2010), Neve et al. (2004) | ||
| S100A10-annexin 2 | Nav1.8 | K2P/TASK | in CFTR | TRP 5, 6, ASC1a, 5-HT1B | van de Graaf et al. (2003), Okuse et al. (2002), Foulkes et al. (2006), Donier et al. (2005), Lotshaw (2007), Girard et al. (2002), Renigunta et al. (2006), Svenningsson et al. (2006) | |
1Abbreviations: Art. memb., Artificial membrane; ASC, acid-sensing ion channel; CFTR, cystic fibrosis transmembrane conductance; hEAG, human ether a go–go K+ channel; 5-HT1B, serotonin receptor; K2P, two-pore domain K+ channel; Kv, voltage gated K+ channel; Nav, voltage gated Na+ channel; RyR, ryanodine receptor; SCG, superior cervical ganglion; SR, sarcoplasmatic reticulum; TASK, TWIK-related Acid Sensitive K+ channel; TRP transient receptor potential.