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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Brain Behav Immun. 2011 Oct 13;26(3):407–413. doi: 10.1016/j.bbi.2011.10.001

Fig. 3.

Fig. 3

Circadian rhythms of mRNA levels in B cells enriched from mouse spleen. Daily oscillations in canonical clock gene expression in B cells enriched from mouse spleen collected every 4 h (ZT3/CT3 = 10 a.m.) (A) under LD conditions and (B) under DD conditions. Relative mRNA levels at each time point were determined by qPCR and calculated as the percentage of the maximum value over the 24-h period. Data are mean ± SEM of 14 or 15 animals per time point, compiled from 3 independent experiments under LD conditions (except n = 9 or 10 for Per1, Clock, and Dbp, compiled from 2 independent experiments) and 4 or 5 animals per time point under DD conditions. a, Significantly different (p < 0.05) from the lowest value; b, significantly different (p < 0.05) from the second lowest value; c, significantly different (p < 0.05) from the third lowest value. Open bar indicates light period, while colored bar indicates dark period.