Table 1.

JTK_CYCLE statistical analyses of the rhythmicity of clock genes in splenic macrophages, dendritic cells, and B cells under LD and DD conditions.

Cell type	Condition	Gene	p valuea	Time of peak expressionb	Amplitude
Macrophages	LD	Per1	< 0.01	13	7.9
		Per2	< 0.001	19	12.7
		Bmal1	= 0.43	13	9.1
		Clock	< 0.05	15	8.5
		Rev-erbα	< 0.0001	15	14.6
		Dbp	< 0.0001	15	20.9
	DD	Per1	= 1.0	3	2.7
		Per2	< 0.05	19	16.7
		Bmal1	= 0.16	3	12.9
		Clock	= 0.50	1	8.1
		Rev-erbα	< 0.01	15	17.6
		Dbp	< 0.01	21	19.1
Dendritic cells	LD	Per1	< 0.001	13	11.0
		Per2	< 0.05	21	10.1
		Bmal1	< 0.01	5	6.1
		Clock	= 1.0	9	1.1
		Rev-erbα	< 0.0001	15	25.2
		Dbp	< 0.0001	17	28.0
	DD	Per1	< 0.01	17	9.8
		Per2	< 0.0001	21	32.8
		Bmal1	= 0.16	1	7.7
		Clock	= 0.06	21	8.9
		Rev-erbα	< 0.0001	17	16.5
		Dbp	< 0.0001	17	21.0
B cells	LD	Per1	< 0.05	17	3.9
		Per2	< 0.0001	19	11.8
		Bmal1	< 0.0001	15	7.1
		Clock	= 1.0	15	1.5
		Rev-erbα	< 0.0001	15	16.5
		Dbp	< 0.01	15	13.0
	DD	Per1	= 0.07	1	4.2
		Per2	= 0.15	1	9.1
		Bmal1	= 0.85	5	2.0
		Clock	< 0.01	11	3.6
		Rev-erbα	< 0.0001	13	15.0
		Dbp	< 0.01	15	10.2

^ap value generated from JTK_CYCLE and adjusted for multiple comparisons.

^bCalculated from JTK_CYCLE output LAG (the number of hours past the first time point that a wave peaks) plus 3.