Table 1.
Credneramide A (1) | Credneramide B (2) | |||||
---|---|---|---|---|---|---|
carbon | δC, mult.a | δH, mult. (J in Hz)b | HMBCb | δC, mult.c | δH, mult. (J in Hz)d | HMBCd |
1 | 172.1, qC | 172.1, qC | ||||
2 | 36.4, CH2 | 2.19, t (7.0) | 1, 3, 4 | 36.4, CH2 | 2.22, t (6.9) | 1, 3, 4 |
3 | 28.4, CH2 | 2.32, dt (7.0, 6.6) | 1, 2, 4, 5 | 28.5, CH2 | 2.35, dt (6.9, 6.1) | 1, 2, 4, 5 |
4 | 131.2, CH | 5.43, dt (15.3, 6.6) | 2, 5, 6 | 131.3, CH | 5.48, dt (14.9, 6.1) | 2, 3, 5, 6 |
5 | 127.8, CH | 5.47, dt (15.3, 6.7) | 3, 4 | 127.8, CH | 5.41, dt (14.9, 6.1) | 3, 4, 6, 7 |
6 | 37.9, CH2 | 2.70, d (6.7) | 4, 5, 7, 8, 11 | 37.9, CH2 | 2.72, d (6.1) | 4, 5, 7, 8, 11 |
7 | 141.5, qC | 141.5, qC | ||||
8 | 32.3, CH2 | 2.15, t (6.7) | 6, 7, 9, 10, 11 | 32.2, CH2 | 2.15, t (7.6) | 6, 7, 9, 10, 11 |
9 | 20.2, CH2 | 1.43 h (7.5) | 7, 8, 10 | 20.2, CH2 | 1.43, h (7.6) | 7, 8, 10 |
10 | 13.9, CH3 | 0.91 t (7.5) | 8, 9 | 13.9, CH3 | 0.91, m | 8, 9 |
11 | 113.1, CH | 5.77, s | 6, 7, 8 | 113.1, CH | 5.78, s | 6, 7, 8, 9 |
NH | 5.42 d (6.2) | 5.39 | ||||
1′ | 40.5, CH2 | 3.53 (dt (6.9, 6.2) | 1, 2′, 3′ | 37.8, CH2 | 3.26, dt (7.2, 6.5) | 1, 2′, 3′ |
2′ | 35.7, CH2 | 2.81, t (6.9) | 1′, 3′, 4′ | 38.5, CH2 | 1.36, dt (7.5, 7.2) | 1′, 3′, 4′, 5′ |
3′ | 138.9, qC | 25.9, CH | 1.60, m | 2′, 4′, 5′ | ||
4′ | 128.7, CH | 7.19, d (7.2) | 2′, 5′, 6′, 7′ | 22.4, CH3 | 0.90, m | 3′, 5′ |
5′ | 128.7, CH | 7.32, dd (7.2) | 3′, 4′ | 22.4, CH3 | 0.90, m | 3′, 4′ |
6′ | 128.5, CH | 7.24, t (7.2) | 4′ | |||
7′ | 128.7, CH | 7.32, t (7.2) | 3′, 4′ | |||
8′ | 128.7, CH | 7.19, d (7.2) | 2′, 5′, 6′, 7′ |
75 MHz in CDCl3.
500 MHz in CDCl3.
150 MHz CDCl3.
600 MHz in CDCl3.