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. Author manuscript; available in PMC: 2013 Mar 21.
Published in final edited form as: J Am Chem Soc. 2012 Mar 9;134(11):5157–5164. doi: 10.1021/ja210399h

Table 1.

Thermodynamics, kinetics, and unfolding/refolding angles of the major transitions in the hTERT 5-12 fragment without the 15-nt hairpin complement at 23 °C.

Transition x (nm) ΔG
(kcal/mol)
ΔG
(kcal/mol)
Angle (°)
42~0 0.33 ± 0.01 18 ± 1 29 ± 2 0.0
42~32 0.33 ± 0.02 3.1 ± 0.6 29 ± 3 86.7
42~25 0.23 ± 0.02 7 ± 1 28 ± 3 −80.0
32~15 0.38 ± 0.02 4 ± 1 10 ± 1 −82.0
25~0 0.37 ± 0.03 4.6 ± 0.1 9 ± 2 78.9
15~0 0.41 ± 0.02 5 ± 1 10 ± 1 −76.3