Fig. 3.
CD151 has little effect on diffusion coefficients. Diffusion coefficients (Dμ and DM), determined as described in the Materials and Methods, are indicated for each condition. Data supporting these bar graphs are shown in supplementary material Table S1, Table S2 and Fig. S3. Left panel: effect of CD151 shRNA; right panel: effect of CD151 siRNA (plus talin siRNA). Prior to adding beads, cells were either unstimulated, or treated with cytochalasin D (cytoD, 10 μM, 1 hour), phorbol 12-myristate 13-acetate (PMA, 0.2 μg/ml, 30 minutes), epidermal growth factor (EGF, 0.02 μg/ml, 1 hour) or methyl-β-cyclodextrin (MβCD, 2 mM, 1 hour). Values are means ± s.e.m. The numbers 1–8 indicate the sample groups.