Figure 1.

Mouse EAR secretion in vivo is correlated with eosinophil infiltration into airways of mouse OVA-challenge model of airway inflammation. RNase (A) or EPO (B) activity was measured in BALF supernatant isolated 4 d after the final challenge of OVA (O)- or PBS (P)-primed and -challenged mice. Mouse groups are depicted as priming/challenge with OVA or PBS (P/P, P/O, O/P, or O/O). Data are means ± sd of relative fluorescence (×10⁴ RFU; A) or OD_{492 nm} (B) acquired from triplicate wells of 3 mice/group. Inset: eosinophil percentage from total cells found in BALFs of OVA- or PBS-primed and -challenged mice (B). Data are representative of 2 independent experiments. P values of enzyme activity or eosinophil percentage in BALF are compared with OVA-primed and -challenged samples.