TABLE 1.
Route | Sex | Time | Urine | Feces | ||
---|---|---|---|---|---|---|
h | % of dose mean | S.D. | % of dose mean | S.D. | ||
Intravenous | M | 0–1 | 22.83 | NC | NS | NC |
1–4 | 11.33 | 6.72 | 0.01 | NC | ||
4–24 | 29.60 | 11.46 | 16.90 | 4.57 | ||
0–24 | 56.15 | 5.13 | 16.90 | 4.57 | ||
Intravenous | F | 0–1 | 15.81 | 5.16 | NS | NC |
1–4 | 6.34 | 2.86 | NS | NC | ||
4–24 | 36.79 | 1.11 | 9.44 | 0.18 | ||
0–24 | 58.94 | 1.87 | 9.44 | 0.18 | ||
M | 0–1 | NS | NC | 0.01 | NC | |
Oral | 1–4 | 0.86 | 0.33 | 0.01 | NC | |
4–24 | 33.73 | 5.20 | 35.71 | 7.40 | ||
0–24 | 34.59 | 5.14 | 35.71 | 7.40 | ||
Oral | F | 0–1 | 0.16 | NC | 0.02 | NC |
1–4 | 2.04 | 1.20 | 0.08 | NC | ||
4–24 | 34.78 | 5.31 | 2.68 | 2.31 | ||
0–24 | 36.88 | 6.26 | 2.72 | 2.34 |
M, male; F, female; NC, not calculated; NS, not significant.