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Mean (±S.D., n = 3) PAN isomer transport in pcDNA3.1-MDCKII (left) or rAbcg2-MDCKII cells (right) at initial donor PAN concentrations of 3, 10, 30, 50, and 200 μM. The isomers were studied individually. Squares, (+)PAN; circles, (−)PAN; closed symbols, basolateral-to-apical flux; and open symbols, apical-to-basolateral flux.
