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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Drug Deliv Transl Res. 2011 May 17;1(3):256–276. doi: 10.1007/s13346-011-0029-z

Fig. 17.

Fig. 17

Shape of the scoring function, the value of which (the score) gives merit to gel spreading performance [10]. In this model, the score is a function of predicted coated area A. Amax is the target coated area, which is the surface area of the vagina. A* is a limiting predicted value of A, which is equal to Amax/[1−VL/V] where V is gel volume, and VL is an upper limit on leaked volume. That is, VL is a maximal value of V at which the value of the score drops to zero. This is set by the user of the model