Table 1. Demographic characteristics of total sample.
| Characteristics |
Tower of London planning task |
Emotional face paradigm |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Genotype | Genotype | |||||||||
| Total | PCLO+ | PCLO− | χ2 | P-value | Total | PCLO+ | PCLO− | χ2 | P-value | |
| Number of subjects | 159 | 110 | 49 | 126 | 90 | 36 | ||||
| Gender (%female) | 64.1 | 64.5 | 63.3 | 0.024 | >0.05 | 61.9 | 61.1 | 63.8 | 0.08 | >0.05 |
| Age (mean years ±s.d.) | 38.17 (10.7) | 37.9 (10.2) | 38.8 (11.9) | >0.05 | 38.1 (10.3) | 38.0 (10.2) | 38.4 (10.7) | >0.05 | ||
| Education (mean years ±s.d.) | 12.5 (3.1) | 12.8 (3.3) | 11.9 (2.8) | >0.05 | 12.6 (3.1) | 12.8 (3.2) | 12.1 (2.8) | >0.05 | ||
| Scan center (A/L/G) | 42/62/55 | 28/46/36 | 14/16/19 | 1.21 | >0.05 | 24/54/48 | 19/40/31 | 5/14/17 | 1.99 | >0.05 |
| Diagnosis (MDD/HC) | 118/41 | 84/26 | 35/15 | 0.86 | >0.05 | 96/30 | 69/21 | 27/9 | 0.04 | >0.05 |
| IDS (mean score ±s.d.) | 18.90 (13.5) | 20.06 (13.2) | 16.27 (14.0) | >0.05 | 19.46 (13.9) | 20.05 (13.6) | 17.91 (14.8) | >0.05 | ||
| MADRS (mean score ±s.d.) | 11.89 (10.4) | 13.01 (10.3) | 9.39 (10.1) | =0.042 | 12.78 (10.4) | 13.53 (10.3) | 10.80 (10.4) | >0.05 | ||
| Duration of SSRI use (months ±s.d.) | 22.91 (37.6) | 27.77 (38.8) | 18.80 (36.5) | >0.05 | 23 (36.9) | 24.75 (37.7) | 18.8 (36.5) | >0.05 | ||
| SSRI use (no/yes) | 119/40 | 82/28 | 37/12 | >0.05 | 92/34 | 67/24 | 25/10 | >0.05 | ||
Abbreviations: HC, healthy controls; IDS, inventory of depressive symptomatology; MADRS, Montgomery–Åsberg Depression Rating Scale; MDD, major depressive disorder; PCLO, piccolo; SSRI, selective serotonin reuptake inhibitor.