Figure 2.
Distribution of DYX1C1 mRNA expression stratified by progesterone receptor status and lymph node involvement. (A) Boxplot of the distribution of DYX1C1 mRNA expression examined by qRT-PCR in the CAHRES cohort between PR-positive and PR-negative tumors. The expression of DYX1C1 is significantly higher in PR-positive tumors. Note that the y-axis is inverted, a lower dCT value indicates higher expression. (B) Boxplot of the distribution of DYX1C1 mRNA expression examined by microarray in the Uppsala cohort between PR-positive and PR-negative tumors. The expression of DYX1C1 is significantly higher in PR-positive tumors. (C) Boxplot of the distribution of DYX1C1 mRNA expression examined by qRT-PCR in the CAHRES cohort between patients with positive lymph node metastasis and negative lymph node metastasis. The expression of DYX1C1 is significantly higher in tumors of lymph node-positive patients. Note that the y-axis is inverted, a lower dCT value indicates higher expression. (D) Boxplot of the distribution of DYX1C1 mRNA expression examined by qRT-PCR in the CAHRES cohort between patients with positive and negative periglandular growth. The expression of DYX1C1 is significantly higher in patients with periglandular growth. Note that the y-axis is inverted, a lower dCT value indicates higher expression.