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Immune responses and protection BLP-PbCSP4. BLP-PbCSP4 induced (A) IgG levels against B-cell epitopes ([PPPPNPND]2x-[NANDPAPP]2x) and (B) IFN-γ response against CTL (SYIPSAEKI) and Th (KQIRDSITEEWS) P. berghei CSP epitopes compared to BLP-PbCSP2. (C) Post-challenge parasitaemia of unprotected BLP-PbCSP4 and two immunized mice. Medians are presented on all plots with individual values. Error bars represent SEM. * = p < 0.05, *** = p < 0.001.
