Fig. 3.

Proportion of GBM with high BF inversely correlates with vascularity. (A) Examples of 2 GBMs with different vascularities and BF histograms. Each horizontal panel shows—from left to right—axial T1 post-contrast MR, Xenon-CT (Xe) BF map with tumor outlined in white, tissue section immunostained for CD105 (endothelium) with hematoxylin counterstain, and the corresponding BF histogram. (B) Plot of percent CD105 immunopositivity vs percent of tumor with BF > 20 mL/100 g/min. (Pearson R = 0.48, P < .01). Scale bars = 50 μm.