Fig. 4.
Multimodal BF histograms indicate intact neurons within GBM. (A) Examples of the 3 patterns of neurofilament immunostain. Each horizontal panel shows—from left to right—neurofilament immunostain (Nfil, brown) with hematoxylin counterstain, axial T1 post-contrast MR image, xenon CT (Xe) BF map with tumor outlined in white, and BF histogram (inset is histogram shape). (B) Extent (left) and pattern (right) of neurofilament immunostaining (each scored between 5 and 25) within GBMs with type I, type II, and type III BF histograms. Mean ± SEM. *P < .05. Scale bar = 50 μm.
