Table 2.

AUC values for disease prediction considering uPA, PAI-1, TF and age¹

Biomarker	Group	N1	AUC
			CA/no CA2	CA/benign2	Abnormal/benign2
uPA+PAI-1	All	79	.72	.75	.74
uPA3	Pre	38	.87	.83	.86
TF4	Post	72	.81	.83	.83
TF+uPA	All	35	.84	.92	.91
TF+uPA+PAI-1	All	24	1.0	1.0	.97

¹AUC: area under the receiver operating curve; uPA: urinary plasminogen activator; PAI (uPA inhibitor)-1, TF: Thomsen-Friedenreich antigen; N = number or sample size. The equivalent values as percent should be multiplied by 100 (i.e., .97 = 97%, and so forth)

²Cancer = ductal carcinoma in situ (DCIS), and invasive cancer; Benign = normal and hyperplasia; Abnormal = atypical hyperplasia, DCIS, and invasive cancer. Age is in all three models

³AUC values for postmenopausal women were lower

⁴previously published data [9]