Table 3.
Accumulated treatment dose (Dacc) deviations relative to the planned static dose (Dplan) and the predicted 4D CT breathing dose (Dpred).
| Accumulated (Dacc) vs. planned (Dplan)
|
Accumulated (Dacc) vs. predicted (Dpred)
|
Dacc-Dplan vs Dacc-Dpred | |||||
|---|---|---|---|---|---|---|---|
| Mean, SD, in Gy | Max, Min in Gy (% of Rx) | Patients with |Δ| ≥ 5% | Mean, SD, in Gy | Max, Min in Gy (% of Rx) | Patients with |Δ| ≥ 5% | ||
| GTV (min to 0.5 cc), n=54 | −0.2, 1.0 | −4.4, 2.3 (−15, 5) | 10% | 0.1, 1.4 | −4.3, 8.1 (−14, 13) | 10% | |
| Liver (mean), n=30 | −0.2*, 0.5 | −1.7, 0.9 (−6, 2) | 3% | −0.1, 0.6 | −1.5, 1.0 (−5, 3) | 3% | |
| Large bowel (max to 0.5 cc), n=30 | −1.1*, 1.5 | −5.3, 1.3 (−15, 3) | 33% | 0.4, 1.7 | −2.3, 5.9 (−7, 10) | 20% | * |
| Small bowel (max to 0.5 cc), n=15 | −1.3*, 2.2 | −7.8, 0 (−26, 0) | 20% | −0.6, 2.1 | −6.5, 1.7 (−22, 5) | 33% | * |
| Duodenum (max to 0.5 cc), n=30 | −1.5*, 2.6 | −12.6, 0.7 (−42, 3) | 33% | −0.2, 2.5 | −11.5, 5.2 (−38, 9) | 7% | * |
| Esophagus (max to 0.5 cc), n=29 | 0.3*, 0.8 | −0.8, 2.4 (−3, 8) | 7% | −0.3, 0.9 | −2.9, 2.0 (−6, 5) | 14% | * |
| Stomach (max to 0.5 cc), n=30 | −0.4, 1.5 | −4.3, 4.6 (−14, 8) | 17% | 0, 1.2 | −3.2, 2.7 (−9, 8) | 20% | * |
| Right kidney (mean), n=30 | −0.4*, 0.7 | −2.0, 0.6 (−5, 2) | 10% | 0, 0.9 | −2.0, 3.9 (−5, 7) | 7% | * |
| Left kidney (mean), n=30 | −0.1, 0.3 | −1.2, 0.4 (−3, 1) | 0% | 0.1, 0.2 | −0.7, 0.6 (−2, 2) | 0% | * |
| Heart (max to 0.5 cc), n=25 | −0.5*, 1.0 | −4.0, 0.8 (−13, 2) | 8% | −1.0*, 1.9 | −8.2, 0.6 (−19, 2) | 16% | * |
| Mean, SD, in % NTCP | Max, Min, in % NTCP | Patients with |Δ| ≥ 5% | Mean, SD, in % NTCP | Max, Min, in % NTCP | Patients with |Δ| ≥ 5% | ||
| Liver (NTCP), n=30 | −0.5, 2.5 | −8.3, 8.0 | 10% | 0.6, 2.4 | −2.1, 9.4 | 7% | |
Abbreviations: SD=standard deviation; NTCP=normal tissue complication probability; GTV=gross tumour volumes.
*
p<0.05 on paired t-test.