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Pharmacokinetic/Pharmacodynamic Parameters and Associated Equations with Covariates for Target-Controlled Infusion of Propofol
V2: 18.9 - 0.391 × (age - 53), Cl1: 1.89 + 0.0456 × (weight - 77) - 0.0681 × (lbm - 59) + 0.0264 × (height - 177), Cl2: 1.29 - 0.024 × (age - 53), Age: age in years, Weight: body weight in kilograms, Height: height in centimeters, Lbm (lean body mass) for women: 1.07 × weight - 148 × (weight / height)2. *Ke0 from the study of Struys et al. [6].
