Table 3.

Categories of posttransplant lymphoproliferative disorders.

(1) Early lesions

(a) Reactive plasmacytic hyperplasia

(b) Infectious mononucleosis-like lesions

(2) Polymorphic PTLD

(3) Monomorphic PTLD (classified according to lymphoma they resemble)

B-cell neoplasms

(a) Diffuse large B-cell lymphoma (DLBCL)

(b) Burkitt's lymphoma

(c) Plasma cell myeloma

(d) Plasmacytoma-like lesions

(e) Others*

T-cell neoplasms

(a) Peripheral T-cell lymphoma not otherwise specified

(b) Hepatosplenic T-cell lymphoma

(c) Others

(4) Classical Hodgkin's lymphoma-type (HL-PTLD) and HL-like PTLD**

*Indolent small B-cell lymphomas developing in transplant recipient are not included among the PTLD.

**HL-like PTLDs are better categorized either as a polymorphic or monomorphic PTLD based on the overall morphology.