Table 3.
Hemodynamic and perfusion parameters in subgroups of patients.
| Lactate < 2.5 mmol/L | Lactate ≥ 2.5 mmol/L | |
|---|---|---|
| Peak lactate level (mmol/l) | 1.7 [1.3–2] | 4.5 [3.4–7.4]** |
| Baseline lactate levels (mmol/l) | 1.2 [1–1.8] | 4 [3–5.8]** |
| Baseline PAOP (mmHg) | 18 [13–26.5] | 19.5 [15.3–23.8] |
| Baseline CI (l/min/m2) | 3.2 [1.9–3.5] | 3 [2.4 –3.7] |
| Lowest CI (l/min/m2) | 2 [1.9–3.2] | 2.4 [2 –2.7] |
| Lowest ScvO2 (%) | 67 [59–71] | 66 [58 –72] |
| Lowest SvO2 (%) | 69 [65 –74] | 68 [61 –75] |
| Peak NE dose (ug/kg/min) | 0.08 [0.04 – 0.17] | 0.2 [0.07–0.53]** |
| NE use (h) | 22 [11–41] | 35 [17–69]* |
| 24 h fluid balance (mL) | 1903 [845–2835] | 4000 [1973–5509]** |
| Cumulative 72 h fluid balance (mL) | 2857 [1130–5264] | 5978 [3674–9551]** |
| Dobutamine use (% of patients) | 18 | 46** |
| Basal P(cv-a)CO2 (mmHg) | 5.5 [3–8] | 6.1 [4.7–8] |
| Peak intra-abdominal pressure (mmHg) | 19 [12.5–24] | 17 [15–19] |
*P < 0.05.
**P < 0.01.
Data are shown as median [interquartile range] or percentage. PAOP: pulmonary artery occlusion pressure; CI: cardiac index; ScvO2: central venous oxygen saturation; SvO2: mixed venous oxygen saturation; NE: norepinephrine; P(cv-a)CO2: central venous-to-arterial PCO2 difference.