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. Author manuscript; available in PMC: 2012 Apr 26.
Published in final edited form as: J Immunol. 2009 Mar 1;182(5):2753–2765. doi: 10.4049/jimmunol.0801124

FIGURE 2.

FIGURE 2

CCR4 expression on Tregs is unique among T cells. Homogenates from both normal and LLC-bearing lung tissue along with normal splenocytes were immunofluorescently stained for CD8, CD4, CD25, FoxP3, and CCR4. A, Representative histograms of CCR4 expression among T cell types. B, Across all types of homogenate, Tregs had significantly higher MFI of CCR4 staining compared with both CD8+ and CD4+CD25− cells (**, p < 0.05 vs CD8+ and CD4+CD25−). Similarly, of all CCR4+ T cells in the homogenates, Tregs comprised a greater percentage as compared with the CD8+ and CD4+CD25− populations (C). In addition, LLC-bearing tissue contains a significantly increased number of CCR4+ Tregs (D).