Table 1.

Top 50 genes negatively correlated with ZEB1 in 38 NSCLC cell lines.

		Spearman R values1
RANK	SYMBOL	ZEB1	ZEB2	SNAIL	SLUG	TWIST1	TWIST2	GENE NAME
1	EPCAM	−0.85	−0.79	−0.19	0.00	−0.20	−0.14	epithelial cell adhesion molecule
2	CDS1	−0.85	−0.69	−0.30	0.19	−0.18	−0.19	CDP-diacylglycerol synthase 1
3	TSPAN1	−0.83	−0.56	−0.22	0.16	−0.16	−0.04	tetraspanin 1
4	ESRP1	−0.82	−0.73	−0.28	0.19	0.01	−0.07	epithelial splicing regulatory protein 1
5	ST14	−0.82	−0.66	−0.24	0.06	−0.11	−0.05	suppression of tumorigenicity 14 (colon carcinoma)
6	SH3YL1	−0.81	−0.75	−0.38	0.09	−0.11	−0.02	SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
7	IRF6	−0.80	−0.58	−0.12	0.24	−0.13	−0.04	interferon regulatory factor 6
8	EPN3	−0.80	−0.46	−0.24	0.26	−0.05	0.03	epsin 3
9	ESRP2	−0.79	−0.59	−0.33	0.04	0.04	−0.02	epithelial splicing regulatory protein 2
10	TMEM125	−0.79	−0.60	−0.11	0.02	−0.30	−0.16	transmembrane protein 125
11	TMEM30B	−0.79	−0.60	−0.12	0.11	−0.17	−0.23	transmembrane protein 30B
12	BIK	−0.79	−0.50	−0.22	0.14	0.00	−0.16	BCL2-interacting killer (apoptosis-inducing)
13	F11R	−0.78	−0.71	−0.25	−0.02	−0.09	−0.09	F11 receptor
14	ITGB6	−0.78	−0.63	−0.23	0.20	−0.26	−0.23	integrin, beta 6
15	PTK6	−0.78	−0.64	−0.12	0.19	−0.09	−0.01	PTK6 protein tyrosine kinase 6
16	EPPK1	−0.77	−0.63	−0.04	0.15	−0.30	−0.16	epiplakin 1
17	MAL2	−0.77	−0.60	−0.26	0.26	0.02	−0.16	mal, T-cell differentiation protein 2
18	PAK6	−0.77	−0.62	−0.07	0.38	−0.10	−0.08	p21 protein (Cdc42/Rac)-activated kinase 6
19	VAMP8	−0.77	−0.44	−0.30	0.19	−0.16	−0.08	vesicle-associated membrane protein 8 (endobrevin)
20	FGFBP1	−0.77	−0.45	−0.11	0.27	−0.12	−0.04	fibroblast growth factor binding protein 1
21	LAD1	−0.77	−0.54	−0.10	0.21	−0.10	−0.16	ladinin 1
22	B3GNT5	−0.76	−0.66	−0.28	0.28	−0.07	−0.03	betaGal beta-1,3-N-acetylglucosaminyltransferase 5
23	FXYD3	−0.76	−0.54	−0.26	0.28	−0.10	0.01	FXYD domain containing ion transport regulator 3
24	GRHL1	−0.75	−0.68	−0.12	−0.08	−0.10	−0.19	grainyhead-like 1 (Drosophila)
25	ADAP1	−0.75	−0.57	−0.07	0.04	−0.13	−0.30	ArfGAP with dual PH domains 1
26	P2RY2	−0.75	−0.48	0.02	0.26	−0.10	−0.05	purinergic receptor P2Y, G-protein coupled, 2
27	S100A14	−0.75	−0.57	−0.18	0.09	−0.13	−0.12	S100 calcium binding protein A14
28	MARVELD3	−0.75	−0.68	−0.20	0.05	−0.02	−0.11	MARVEL domain containing 3
29	ANKRD22	−0.75	−0.55	−0.16	0.13	−0.19	−0.23	ankyrin repeat domain 22
30	HOOK1	−0.75	−0.71	−0.32	−0.14	−0.06	−0.13	hook homolog 1 (Drosophila)
31	CDH1	−0.75	−0.64	−0.10	−0.15	−0.25	−0.21	cadherin 1, type 1, E-cadherin (epithelial)
32	MPZL2	−0.74	−0.63	−0.13	0.11	−0.24	−0.04	myelin protein zero-like 2
33	MAPK13	−0.74	−0.66	−0.11	0.18	−0.06	−0.17	mitogen-activated protein kinase 13
34	GPR87	−0.74	−0.45	−0.12	0.42	0.04	−0.08	G protein-coupled receptor 87
35	ZNF165	−0.74	−0.56	−0.29	0.35	0.01	0.01	zinc finger protein 165
36	ELMO3	−0.74	−0.67	−0.11	0.08	−0.26	−0.19	engulfment and cell motility 3
37	EXPH5	−0.74	−0.66	−0.10	−0.07	−0.33	0.08	exophilin 5
38	RAB25	−0.73	−0.60	−0.17	0.06	−0.30	−0.29	RAB25, member RAS oncogene family
39	TACSTD2	−0.73	−0.55	−0.21	0.15	−0.13	−0.22	tumor-associated calcium signal transducer 2
40	LIMA1	−0.73	−0.51	−0.23	0.04	−0.09	−0.15	LIM domain and actin binding 1
41	CDH3	−0.73	−0.63	0.10	0.09	−0.25	−0.12	cadherin 3, type 1, P-cadherin (placental)
42	TMPRSS4	−0.72	−0.60	0.00	0.00	−0.24	−0.22	transmembrane protease, serine 4
43	QSOX1	−0.72	−0.64	−0.31	0.03	−0.11	−0.21	quiescin Q6 sulfhydryl oxidase 1
44	SPINT1	−0.72	−0.61	−0.15	0.07	−0.18	−0.19	serine peptidase inhibitor, Kunitz type 1
45	CLDN7	−0.72	−0.57	−0.12	0.02	−0.37	−0.22	claudin 7
46	LOC283278	−0.72	−0.51	−0.21	0.09	−0.09	0.01	hypothetical protein LOC283278
47	CRB3	−0.71	−0.71	−0.43	0.03	−0.09	−0.07	crumbs homolog 3 (Drosophila)
48	FGD4	−0.71	−0.30	−0.23	0.10	0.08	−0.23	FYVE, RhoGEF and PH domain containing 4
49	BSPRY	−0.71	−0.63	−0.06	−0.06	−0.30	−0.30	B-box and SPRY domain containing
50	PKP3	−0.71	−0.56	−0.36	0.33	0.11	0.14	plakophilin 3

¹Significant R values are bolded and italicized. Genes of interest are highlighted in gray.