Skip to main content
. Author manuscript; available in PMC: 2012 Apr 26.
Published in final edited form as: Cancer Lett. 2010 Oct 25;300(1):66–78. doi: 10.1016/j.canlet.2010.09.007

Table 4.

Changes in gene expression induced by knockdown of ZEB1, ZEB2, or both in NSCLC cell lines.

siRNA ZEB1 ZEB2 E-cad EpCAM ESRP1 ESRP2 CDS1 ST14 FGFR1 Vimentin
H157 ZEB1 0.23 2.1 2.5 0.79 3.4 2.3 1.7 7.1 3.7 0.94
ZEB2 0.72 0.10 0.20 1.4 2.2 4.8 0.29 1.4 1.5 1.2
ZEB1 + ZEB2 0.36 0.15 18 74 164 3.7 7.3 16 2.5 0.8

H460 ZEB1 0.27 1.0 179 20 1.9 1.3 4.2 3.8 1.8 1.2
ZEB2 1.0 0.21 0.65 1.7 0.85 1.8 1.3 1.2 1.2 1.5
ZEB1 + ZEB2 0.33 0.25 2280 139 4.5 2.5 10 12 2.7 1.9

H661 ZEB1 0.25 1.1 3.7 1.6 1.1 0.86 2.1 1.5 1.0 0.85
ZEB2 1.4 0.18 1.9 1.7 2.0 1.4 1.7 0.53 1.2 1.0
ZEB1 + ZEB2 0.41 0.33 32 3.4 6.2 1.4 3.8 0.38 1.7 1.3

A549 ZEB1 0.27 0.16 1.6 4.0 2.5 0.86 2.4 2.4 0.29 0.36
ZEB2 0.68 0.06 0.49 0.74 0.62 0.33 0.76 1.4 0.47 0.53
ZEB1 + ZEB2 0.26 0.11 2.5 2.6 4.2 0.32 2.5 1.4 0.69 0.59
graphic file with name nihms246370t2.jpg