Table 1.
Lesions in vein graft and artery proximal and distal to the graft
| Segment | Artery proximal to grafta | Vein grafta | Artery distal to graft |
|---|---|---|---|
| Lesion type b | |||
| Normal intima or adaptive intimal thickeningc | 1 (12.5%) | 5 (62.5%) | 8 (89%) |
| Intimal xanthoma (fatty streak)d | 7 (87.5%) | 0 | 1 (11%) |
| Plaque without necrotic coree | 0 | 1 (12.5%) | 0 |
| Plaque with necrotic coref | 0 | 2 (25%) | 0 |
| Lesion thickness | |||
| Intimal (vein graft wall) thickness in μmg | 82 (47)h | 712 (276) | 26 (32)h |
Lesion types are given as count (frequency) and lesion thickness as mean (standard deviation)
a n = 8: thrombosed segments were not classified
b The distribution of lesion types differ between the three segments (P < .01) and also between the two arterial segments (P < .01)
c Lesion consisting of normal connective tissue containing smooth muscle cells. No lipid accumulation or macrophages
d Lesion consisting of normal intima except foam cell accumulation near lumen
e Lesion with extracellular accumulation of lipid and connective tissue with fibrosis with or without calcification. No lipid-rich necrotic core
f Lesion containing a lipid-rich necrotic core
g In the vein grafts, the intima-media border is ill-defined and intima and media were considered together in the vein grafts
h Intimal thickness was significantly different between the arterial segments (P < .05)