. Author manuscript; available in PMC: 2013 Feb 3.

Published in final edited form as: J Org Chem. 2012 Jan 24;77(3):1554–1559. doi: 10.1021/jo201910g

TABLE 2.

Metal ion-promoted decomposition of 2.^a

catalyst (in D₂O)	reaction time	unreacted	product yields

		2	3^b	4
/	24 h	/	43%	11%
PBS buffer (200 mM)	0.5 h	/	15%	30%
Fe³⁺ (3.6 mM)	0.5 h	/	70%	5%
Cu²⁺ (3.6 mM)	0.5 h	/	80%	9%

^(a)

36 mM at 37 °C.

^(b)

as the hydrate 13.