Table 1.
Baseline characteristics of subjects in study of UAGT in obese individuals
Variable | Group I (n=39) |
Group II (n=38) |
P value |
---|---|---|---|
Age (years) | 31.7 ± 10.2 | 40.0±12.6 | <0.01 |
BMI | 23.0±2.8 | 38.2±5.6 | <0.01 |
UAGT/UCr (μg/g) | 6.3±4.3 | 5.2±3.3 | NS |
Serum creatinine (mg/dL) | 0.8±0.2 | 0.8±0.2 | NS |
UALB/UCr (mg/g) | 8.5±7.2 | 11.0±10.7 | NS |
Glucose (mg/dL) | 60.8±19.3 | 79.7±26.1 | <0.01 |
Systolic BP (mm Hg) | 117.6±11.9 | 127.0±15.7 | <0.01 |
Diastolic BP (mm Hg) | 72.3±12.0 | 79.4± 11.6 | 0.01 |
HDL cholesterol (mg/dL) | 60.9±13.4 | 52.0±17.2 | 0.02 |
LDL cholesterol (mg/dL) | 93.3±28.3 | 119.1 ±36.4 | <0.01 |
Triglycerides (mg/dL) | 70.4±24.2 | 128.7±5.1 | <0.01 |
Group I = nonobese controls (BMI ≤27); Group II = obese subjects (BMI ≥30). No subjects had diabetes or hypertension
Values are expressed as mean ± standard deviation
UAGT urinary angiotensinogen, BMI body mass index, UCr urinary creatinine, NS not significant, UALB urinary albumin, BP blood pressure, HDL high-density lipoprotein, LDL low-density lipoprotein