Skip to main content
. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Dev Biol. 2011 Jul 23;358(1):168–180. doi: 10.1016/j.ydbio.2011.07.027

Figure 7. Dsulf1 expression is regulated by EGFR signalling.

Figure 7

(A, A') Dsulf1 expression (red in A) detected in late 3rd instar wing disc containing clonal cells (green) over-expressing an active form of Ci (CiAct). Note that Dsulf1 expression is not detected within the clone but is activated ectopically, in cells adjacent to Flp>CiAct cells (arrowhead in A and A’). (B, B') Dsulf1 expression (red in B) detected in late 3rd instar wing disc containing a clone of cells expressing a dominant-negative form of EGFR, marked by GFP (Flp>EGFRDN, green). Note the repression of endogenous Dsulf1 expression within Flp>EGFRDN clones. (C-D) Wing discs expressing a constitutively activated form of the EGF receptor (ap>EGFRCA, C) or Rhomboïd (ap>Rho, D) in the dorsal compartment display an autonomous ectopic up-regulation of Dsulf1 expression.