Table 7.
Genes encoding proteins involved in steroid metabolism, stress responses and apoptosis
| Gene | C0 | CL | SL |
|---|---|---|---|
| Steroid metabolism | |||
| 11-beta-hydroxysteroid dehydrogenase | 1.70 | 1.86 | NS |
| 7-dehydrocholesterol reductase | 1.05 | NS | NS |
| Cholesterol 25-hydroxylase-like protein A | 1.92 | 1.70 | 0.87 |
| Cytochrome P450 3A27 | 0.81 | 0.60 | NS |
| Diphosphomevalonate decarboxylase | 1.02 | 0.66 | NS |
| FK506 binding protein 5 | 2.30 | 2.52 | 0.58 |
| FK506-binding protein 5 | 2.47 | 2.93 | 0.69 |
| Vitamin D3 hydroxylase-associated | 0.82 | 0.73 | NS |
| Amino acids metabolism | |||
| Arginase-2 mitochondrial | 0.97 | NS | -0.11 |
| Arginine N-methyltransferase 5 | 1.06 | 0.63 | 0.25 |
| Ornithine decarboxylase 1 | 1.43 | 1.27 | 0.86 |
| Diamine acetyltransferase 1 | -0.87 | -0.98 | 0.29 |
| Glutamate decarboxylase-like 1 | 3.17 | 3.66 | 1.24 |
| Glutaminase | -1.02 | -0.76 | 0.32 |
| Glutamine synthetase | 1.14 | 0.86 | 0.00 |
| Lysine ketoglutarate reductase | 0.98 | 0.98 | -0.14 |
| Apoptosis | |||
| CCAAT/enhancer-binding protein beta | 2.05 | 1.62 | 0.62 |
| CCAAT/enhancer-binding protein delta | 1.16 | 1.15 | NS |
| Jun-B | 1.14 | 0.99 | NS |
| GADD45 alpha | 1.27 | 1.32 | NS |
| GADD45 beta | 1.54 | 1.80 | 0.66 |
| Arrestin domain-containing protein 2 | 0.87 | 0.81 | NS |
| Caspase-3 | 1.07 | 0.93 | NS |
| Heme-binding protein 2 | 1.61 | 1.77 | NS |
| Programmed cell death 1 ligand 1 | -1.09 | -0.84 | 0.49 |
| Oxidative and protein stress | |||
| Glutathione peroxidase 7 | -2.59 | -1.72 | 0.63 |
| Glutathione peroxidase type 2 | 1.36 | 1.20 | NS |
| Glutathione reductase mitochondrial | 0.97 | 0.67 | NS |
| Heat shock cognate 70 kDa protein | 1.39 | 1.60 | NS |
| Heat shock cognate 70 kDa protein | 1.15 | 0.93 | NS |
| Heat shock cognate 71 kDa protein | 1.14 | 0.79 | NS |
| Heat shock protein 47 kDa | -2.01 | -1.43 | 0.61 |
| Heat shock protein 60 kDa | 1.31 | 0.94 | NS |
| Heat shock protein 70 kDa | -1.50 | -1.08 | -1.40 |
| Heat shock protein 90 kDa | -0.31 | -0.23 | -0.87 |
| 78 kDa glucose-regulated protein | 0.57 | 1.06 | 0.82 |
| Transporters | |||
| Solute carrier family 1, member 4 | 1.90 | 1.77 | 0.55 |
| Solute carrier family 25 member 33 | 0.58 | 0.71 | NS |
| Solute carrier family 25-2 | -1.00 | -0.35 | -0.96 |
| Taurine transporter | 1.59 | 2.21 | NS |
| ATP-binding cassette A12 | 1.73 | 1.38 | NS |
| ATP-binding cassette B6 | 0.88 | 0.68 | NS |
| ATP-binding cassette C1 | -2.28 | -1.65 | 0.40 |
| ATP-binding cassette E1 | 0.70 | 0.62 | NS |
| ATP-binding cassette F3 | 0.86 | 0.85 | 0.46 |
| Multidrug resistance associated protein 2 | -1.28 | -0.98 | 0.46 |