Table 3.

Univariate analysis of Clinicopathological features, tumor markers, and patient survival

Variable	PFS HR (95% CI)	P value	OS HR (95% CI)	P value
Gender (Male vs. Female)	1.370 (0.744-2.524)	0.313	1.341 (0.713-2.421)	0.381
Age (≤ 60 vs.>60)	1.433 (0.789-2.604)	0.237	1.450 (0.798-2.635)	0.223
Nationality (The Han vs. The Zhuang)	0.929 (0.480-1.800)	0.827	0.964 (0.497-1.867)	0.912
Histology (Squamous carcinoma vs. Adenocarcinoma)	0.541 (0.267-1.095)	0.088	0.559 (0.276-1.133)	0.106
Differentiation (Well and moderate vs. Poor)	0.992 (0.528-1.866)	0.980	0.953 (0.506-1.795)	0.881
Metastasis lymphatics (Yes vs. No)	0.429 (0.236-0.780)	0.006**	0.435 (0.238-0.793)	0.007**
TNM stage (I+II vs. III+IV)	2.267 (1.257-4.090)	0.007**	2.217 (1.227-4.003)	0.008**
ERCC1 (positive vs. negative)	0.326 (0.165-0.645)	0.001**	0.333 (0.169-0.660)	0.002**
BAG-1 (positive vs. negative)	0.367 (0.202-0.665)	0.001**	0.363 (0.200-0.658)	0.001**
BRCA1 (positive vs. negative)	0.546 (0.270-1.105)	0.093	0.505 (0.250-1.021)	0.057
RRM1 (positive vs. negative)	0.539 (0.314-1.143)	0.120	0.590 (0.309-1.126)	0.110
TUBB3 (positive vs. negative)	0.665 (0.319-1.383)	0.275	0.701 (0.338-1.458)	0.342

** represent P < 0.01