Table 3.
Variable | PFS HR (95% CI) | P value | OS HR (95% CI) | P value |
---|---|---|---|---|
Gender (Male vs. Female) | 1.370 (0.744-2.524) | 0.313 | 1.341 (0.713-2.421) | 0.381 |
Age (≤ 60 vs.>60) | 1.433 (0.789-2.604) | 0.237 | 1.450 (0.798-2.635) | 0.223 |
Nationality (The Han vs. The Zhuang) | 0.929 (0.480-1.800) | 0.827 | 0.964 (0.497-1.867) | 0.912 |
Histology (Squamous carcinoma vs. Adenocarcinoma) | 0.541 (0.267-1.095) | 0.088 | 0.559 (0.276-1.133) | 0.106 |
Differentiation (Well and moderate vs. Poor) | 0.992 (0.528-1.866) | 0.980 | 0.953 (0.506-1.795) | 0.881 |
Metastasis lymphatics (Yes vs. No) | 0.429 (0.236-0.780) | 0.006** | 0.435 (0.238-0.793) | 0.007** |
TNM stage (I+II vs. III+IV) | 2.267 (1.257-4.090) | 0.007** | 2.217 (1.227-4.003) | 0.008** |
ERCC1 (positive vs. negative) | 0.326 (0.165-0.645) | 0.001** | 0.333 (0.169-0.660) | 0.002** |
BAG-1 (positive vs. negative) | 0.367 (0.202-0.665) | 0.001** | 0.363 (0.200-0.658) | 0.001** |
BRCA1 (positive vs. negative) | 0.546 (0.270-1.105) | 0.093 | 0.505 (0.250-1.021) | 0.057 |
RRM1 (positive vs. negative) | 0.539 (0.314-1.143) | 0.120 | 0.590 (0.309-1.126) | 0.110 |
TUBB3 (positive vs. negative) | 0.665 (0.319-1.383) | 0.275 | 0.701 (0.338-1.458) | 0.342 |
** represent P < 0.01