Table 2.
Selected ongoing phase III trials of systemic therapy in operable gastric cancer
| Trial name (no of patients planned) | Eligible population | Treatment arms |
|---|---|---|
| ST03[50] (950) | Stage Ib-IV resectable adenocarcinoma of the stomach or GOJ | Perioperative ECX 3 cycles before and 3 after surgery |
| Perioperative ECX + bevacizumab 3 cycles before and 3 after surgery followed by maintenance bevacizumab for 6 cycles. | ||
| CRITICS[40] (788) | Stage Ib-IV gastric cancer | Perioperative ECX chemotherapy before and after surgery |
| Preoperative ECX chemotherapy then adjuvant CX chemoradiation | ||
| SAMIT[41] (1495) | T3/T4 gastric carcinoma | Adjuvant S-1 for 11 months |
| Adjuvant UFT for 11 months | ||
| Adjuvant paclitaxel for 3 months followed by UFT for 8 months | ||
| Adjuvant paclitaxel for 3 months followed by UFT for 8 months |