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. Author manuscript; available in PMC: 2012 Apr 27.
Published in final edited form as: Nat Genet. 2010 Nov 14;42(12):1068–1076. doi: 10.1038/ng.716

Figure 1. Manhattan plot.

Figure 1

Manhattan plot showing the association of SNPs with QRS interval duration in a GWAS of 40,407 individuals. The dashed horizontal line marks the threshold for genome-wide significance (P = 5 × 10−8). Twenty loci (labeled) reached genome-wide significance. Two additional loci, GOSR2 and DKK1, reached significance after genotyping of select SNPs in an additional sample of 7170 individuals (see Results).