Table 2.

Multivariate regression model predicting time-averaged albuminuria (g/24 hr)

Variable	Regression Coefficient for Change in Time-Averaged Albuminuria (95% CI)	P Value for Trend
Per increase in log FGF23 (RU/ml)	0.26 (0.05–0.47)	0.02
Per 10 ml/min/1.73 m2 of eGFR	−0.05 (−0.10 to −0.005)	0.03
Per 0.1 mmol/L of calcium	−0.24 (−0.35 to −0.13)	<0.001
Per 1 g/24 hours of albuminuria	0.45 (0.34–0.57)	<0.001

In a stepwise regression model log, fibroblast growth factor-23 (FGF23), age, sex, serum albumin, baseline albuminuria, baseline estimated GFR (eGFR), calcium, phosphate, parathyroid hormone, 25-hydroxyvitamin D, mean arterial BP, body mass index, and use of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers were included. Log FGF23, eGFR, calcium, and albuminuria were retained as significant (adjusted R² = 0.44 for the whole model, P<0.001). The regression coefficients are adjusted for the listed variables. CI, confidence interval; RU, relative units.