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The structure of the second domain of gelsolin (G2) in the absence of calcium. Residue 187 is the mutation site in FAF, and residues 173–243 (gold) comprise the amyloid fragment. Fersht and coworkers studied a fragment comprising residues 151–266 (green and gold) and Ratnaswamy et al. examined the entire G2, residues 134–266 (blue, green and gold) (3, 5).
