Table 2.
Twelve-Month Outcomes by Site
| Lighthouse | Mzuzu | QECH | Thyolo | Total | |
| (n = 150) | (n = 147) | (n = 149) | (n = 147) | (N = 593) | |
| Outcome | |||||
| Dead | 16 (10.7) | 12 (8.2) | 10 (6.7) | 11 (7.5) | 49 (8.3) |
| Defaulted | 9 (6.0) | 20 (13.6) | 26 (17.5) | 12 (8.2) | 67 (11.3) |
| Transferred out | 13 (8.7) | 8 (5.44) | 14 (9.4) | 7 (4.7) | 42 (7.1) |
| Alive on ART | 112 (74.7) | 108 (73.5) | 99 (66.4) | 117 (79.6) | 436 (73.5) |
| Appointment-keeping among those alive | |||||
| ≥80% of the time | 112 (100) | 96 (90.6) | 89 (89.9) | 108 (93) | 405 (93.5) |
| No. with viral load results | 111 (99.1) | 83 (77.6) | 94 (95.8) | 107 (92.2) | 395 (91.2) |
| HIV RNA level | |||||
| Not detected | 97 (87.4) | 76 (91.6) | 88 (93.6) | 99 (92.5) | 360 (91.1) |
| 150–1000 copies/mL | 5 | 1 | 0 | 0 | 6 |
| >1000 copies/mLa | 9 | 6 | 6 | 8 | 29 |
| Denominator for analysis (baseline participants excluding those who died or transferred out) | 121 | 128 | 125 | 129 | 503 |
| HIVDR prevention = viral suppression <1000 copies/mL | 102 (84.2) | 77 (60.1) | 88 (70.4) | 99 (67.3) | 366 (72.7) |
| Any detectable resistanceb | 8/109 (7.3) | 5/82 (6.1) | 3/94 (3.2) | 8/107 (7.5) | 24/392 (6.1) |
| NRTI resistance | 7/109 (6.4) | 3/82 (3.7) | 3/94 (3.2) | 6/107 (5.1) | 19/392 (4.8) |
| NNRTI | 6/109 (5.5) | 5/82 (6.1) | 3/94 (3.2) | 8/107 (7.5) | 23/392 (5.9) |
| PI resistance | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Possible resistance defined by detectable HIV RNA but no resistance mutations | 6/121 (5.0) | 2/128 (1.6) | 3/125 (2.4) | 0 | 11/503 (2.2%) |
| Possible resistance defined by default | 9/121 (7.4) | 20/128 (15.6%) | 26/125 (20.1) | 12/129 (9.3) | 67/503 (13.3) |
Data are no. (%).
Abbreviations: ART, antiretroviral therapy; HIV, human immunodeficiency virus; HIVDR, human immunodeficiency virus drug resistance; NNRTI, nonnucleoside reverse transcriptase inhibitor; NRTI, nucleoside reverse transcriptase inhibitor; PI, protease inhibitor; QECH, Queen Elizabeth Central Hospital.
a
WHO guidelines define suppressed as more than 1000 copies/mL.
b
The denominator indicates the number genotyped.