Blood glucose, body weight, insulin, and blood pressure in control mice and diabetic mice treated with and without (None) AG1478 (AG) or U0126 (U0). A: Comparison of blood glucose levels between control and diabetic mice with or without AG1478 or U0126, n = 10. B: Comparison of body weight between control and diabetic mice with or without AG1478 or U0126, n = 10. C: Serum insulin levels in all groups, (n = 10); *P < 0.05 for diabetic versus control mice. D: Blood pressure measurements with tail-cuff methods in all groups, n = 10.