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. 2012 Jan;180(1):410–418. doi: 10.1016/j.ajpath.2011.09.016

Figure 4.

Figure 4

Quantitative reverse transcription-PCR assessment of (A) MAPK1 (n = 5), (B) EGFR (n = 5), (C) eNOS (n = 5), and (D) VEGF (n = 5) mRNA levels in ischemic hind-limb muscles in control and diabetic mice with or without AG1478 or U0126. The mRNA level was normalized to 18S rRNA as endogenous control. A–D: Results are expressed as the relative expression of mRNA compared to nontreated control mice; *P < 0.05 for diabetic versus control, †P < 0.05 for diabetic versus diabetic treated with U0126 (U0), and ‡P < 0.05 indicating a significant difference between diabetic versus diabetic treated with AG1478 (AG).