Table 2. Pearson's correlation coefficient values (R) obtained from the linear regression analyses correlating myocardial mRNA expression levels of collagen I (Col I), collagen III (Col III), fibronectin 1 (FN), β-Myosin heavy chain (β-MHC) and α-Myosin heavy chain (α-MHC) with the following echocardiographic and tissue Doppler parameters: LV mass; LV ejection fraction (LVEF); mitral annular plane systolic excursion (MAPSE); peak early transmitral flow velocity (E) to peak early myocardial tissue velocity (E′) ratio.
Col I | Col III | FN1 | β-MHC | α-MHC | ||
LV mass | Female | 0.40* | 0.48** | 0.43** | 0.15 | −0.60*** |
Male | 0.54*** | 0.54*** | 0.46*** | 0.13 | −0.56** | |
LVEF | Female | −0.36 | −0.24 | −0.37 | −0.05 | 0.45* |
Male | −0.69*** | −0.65*** | −0.64*** | −0.39 | 0.41* | |
MAPSE | Female | −0.61*** | −0.45*** | −0.57*** | −0.42 | 0.50** |
Male | −0.61*** | −0.63*** | −0.42* | −0.26 | 0.44* | |
E/E′ | Female | 0.69*** | 0.50* | 0.52* | 0.57* | 0.11 |
Male | 0.69*** | 0.70*** | 0.53** | 0.52* | −0.23 |
The correlations include individuals (minimum 25) from each experimental condition.