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. 2012 Apr 25;7(4):e35751. doi: 10.1371/journal.pone.0035751

Figure 5. Regional cerebral blood flow (rCBF) in cerebral cortex of NT and Tg mice in Studies I and II obtained by Laser Doppler measurements at the end of their 2 month and 12-day EMF treatment periods, respectively.

Figure 5

(Fig. 5A) At 2 months into EMF treatment for Study I, APPsw transgenic (Tg) mice exhibited a significant 13% decrease in rCBF during ON vs. OFF periods. During ON periods, an even greater reduction in rCBF for EMF-treated Tg mice was evident when compared to Tg controls. *p<0.05 vs. OFF period by paired t-test. (Fig. 5B) Evaluation of rCBF results from Study I irrespective of genotype revealed that EMF-treated mice had significantly reduced rCBF during both ON and OFF periods. ★p<0.05 vs. No EMF; ★★p<0.0001 vs. No EMF. (Fig. 5C) At 12 days into EMF treatment for Study II's APPsw+PS1 (Tg) mice, a near-significant rCBF reduction of 19% was present in EMF-treated Tg mice during ON vs. OFF periods. †p = 0.10 for ON vs. OFF (paired t-test); #p<0.05 vs. Tg control during OFF period.