Table 5. Comparison of the tumor characteristics of the Central_no group of lesions with the Central and Peripheral groups of lesions.

	Central+Peripheral	Centralno	P value
	Mean (Std. dev.)	Mean (Std. dev.)
GTV (cm)	3.74 (1.49)	5.72 (1.96)	<.0001
GTV_cc	16.4 (21.5)	51.1 (54.4)	0.0065
PTV (cm)	4.90 (1.48)	6.71 (1.97)	<.0001
PTV_cc	43.2 (38.9)	88.7 (74.7)	0.0100
# of separate group of OARs	1.66 (0.81)	3.45 (1.34)	<.0001
Distance to adjusted structures (GTV cm)	0.88 (0.54)	0.26 (0.22)	<.0001
Distance to adjusted structures (PTV cm)	0.48 (0.36)	0.19 (0.18)	0.0001

Central+Peripheral: central and peripheral lesions for which all the dose constraints were met. Central_no: central lesions for which ≥1 dose constraints were not met. Std. dev.: standard deviation. GTV: gross tumor volume. PTC: planning target volume. #: number. cm: centimeter. cc: cubic centimeter. OARs: organs at risk.